Archives: Jargon
Toxicity
The degree to which a medicine is poisonous. How much of a medicine can be taken before it has a toxic effect.
Topic identification
Activities carried out to identify suitable topics for research. These activities provide a way for individuals and groups to propose areas where good evidence is lacking or unanswered questions exist.
Themed call
A call for proposals in a particular area of medicine or health (e.g. obesity, dementia).
Technology Assessment Review (TAR)
A systematic assessment of an intervention (or group of interventions), usually undertaken for policy customers such as NICE.
Substantial Amendment
A substantial amendment can be defined as an amendment to the protocol or any other study specific documentation, the terms of the REC application or the terms of the CTA application (as applicable) that is likely to affect to a significant degree the: The safety or physical or mental integrity of the subjects of the …
SSI
Site Specific Information: local detail to inform SSA including qualifications/expertise of the PI and wider research team, study procedures, departmental capacity to absorb project (includes Pharmacy, Pathology, Radiology) and departmental leads signatures; The SSI form is completed in IRAS
SSA
Site Specific Assessment: An assessment performed to establish the suitability of a Principal Investigator and a site for the conduct of research; SSA will be performed by the Participating CLRN for each research site (NHS organisation), using an SSI form available in IRAS
