This jargon buster or glossary of words contains the definitions of some of the terms commonly used in public involvement in research. It is not a complete list of all the words you might come across. The original definitions were developed for INVOLVE by TwoCan Associates working in consultation with a panel of researchers and a panel of people who use services, and we add to them continually.
The jargon buster can be searched by clicking on one of the letters below or browsing all terms.
Diarrhoea and Vomiting
Devices for Dignity Healthcare Technology Cooperative
Database of Abstracts of Reviews of Effects
Data is the information collected through research. It can include written information, numbers, sounds and pictures. It is usually stored on computer, so that it can be analysed, interpreted and then communicated to others, for example in reports, graphs or diagrams.
A committee that may be established by the sponsor to assess at intervals, the progress of a clinical trial, the safety data, and the critical efficacy endpoints, and to recommend to the sponsor whether to continue, modify, or stop a trial.
All personal information is protected in the UK by the Data Protection Act (1998). This means that researchers have to put in all the necessary safeguards to protect the confidentiality of the information they collect about research participants. They should explain in the patient information sheet:• how the participants’ data will be collected• how it will be stored securely• what it will be used for• who will have access to the data that identifies participants• how long it will be kept• how it will be disposed of securely.
Diagnostic Evidence Cooperatives
A list of appropriately qualified persons to whom the investigator has delegated significant trial related duties.
Sponsors/host organisations will usually provide a template for the Delegation Log and researchers should check with their NHS R&D office if any ‘preferred template’ is available. If no default document is available, the following template may be adapted (pdf, 27.25 KB)
Dementia Translational Research Collaboration
Dementias and Neurodegenerative Diseases Research Network
The common format for annual safety reports on investigational drugs in the ICH regions under ICH guideline E2F.
Department of Health
This is a definition that has been agreed by the EME, PHR, HTA, RfPB and i4i programmes. A diagnostic test is an indicator or predictor of an illness state. As such, the term needs to be interpreted broadly as it includes diagnostic tests, screening, tests to stage disease, treatment monitoring, and estimate prognosis estimation. There are a number of types of diagnostic study that will be considered by the NIHR:
Database of Individual Patient Experience – the DIPEx website has a range of open source videos of real patient experiences www.healthtalkonline.org
Dissemination involves communicating the findings of a research project to a wide range of people who might find it useful. This can be done through:• producing reports (often these are made available on the Internet)• publishing articles in journals or newsletters• issuing press releases• giving talks at conferences.
It is also important to feedback the findings of research to research participants.
Pre-2004 Clinical Trial Arrangements: former method for the approval of a clinical trial by the MHRA now replaced by the Clinical Trial Authorisation.
A trial where the investigators and the subjects included in the trial (healthy volunteers or patients) do not know which interventions / treatments have been assigned.
Doctoral Research Fellowships