Research project
Title: Neuroleptics in adults with aggressive challenging behaviour and intellectual disability (NACHBID)
Project timescale: From 01 July, 2002 to 30 September, 2006
(Added to website on: 18 October, 2004 - Date last updated: 20 April, 2007)
Source of funding:
National Co-ordinating Centre for Health Technology Assessment (NCCHTA)
Aims: 1. To carry out a three-arm controlled trial of a typical neuroleptic drug haloperidol, an atypical neuroleptic drug risperidone and a placebo in non-psychotic patients under treatment from learning disability services. 2. To compare short and long term outcomes in terms of reduction in aggressive challenging behaviour( primary outcome), improved quality of life reduction in burden of carers and cost of care ( secondary)
Research designs used:
Randomised controlled trial
Methods used to collect data:
Validated instruments eg Outcome measures
Research project description: NACHBID is a multi-centre three-arm parallel design, double blind, randomised controlled trial of placebo, halsperidol and resperidone. The sample group includes people with intellectual disability in community settings e.g.. Family homes, supported housing and NHS residential facilities, with living situation stratified at randomisation. Target population - all referrals to community services with mild, moderate or severe learning disability showing aggressive challenging behaviour in absence of a diagnosis of psychotic disorder.
Stages at which the public were involved:
Planning the research
Disseminating research
Other: Promoting research
Description of public involvement in research stages: Mrs Slater of the carer's forum helped in the design of the patient and carer's information sheets. The Harrow user's forum help in study promotion and dissemination of information about the study to other users, carers and at meetings.
Training and support provided for either members of the public or researchers involved in the project:
Examples of ways the public have made a difference to the research project: Help promote study to other users making them aware of projects. a) to create large coloured hand outs describing the process of the trial so that this can be explained more easily by the researchers. b) to give answers from the user perspective to questions from patients before enrolment or already involved in the study. c) meet regularly as a group with researchers to discuss any problems with the trial d) to take part in in "road shows" or other events advertising the trial.
Evaluating the impact of public involvement in the research:
Details of publications or reports resulting from the research: No Articles currently available Publications planned and conferences for dissemination
Was/is your project user controlled: Not Known
For further information on the project, please contact:
Professor Peter Tyrer
Lead Investigator
Imperial College London
Department of Psychological Medicine
The Claybrook Centre
Charing Cross Campus
London
W6 8RP
0207386 1233
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